Harnessing Antisense & RNA Chemistry, with Optimized Delivery & Reduced Toxicity, to Target Undruggable CNS Diseases

Heralding a New Era of CNS-Targeted Oligonucleotides to the Clinic & Beyond

Uniting CNS Biotech & Pharma to Fuel the Next Wave of Oligonucleotide Drug Discovery, Translation & Clinical Progress

With clinical momentum from Eli Lilly’s lipidated brain shuttle siRNAs, Alnylam Pharmaceuticals’ ALN-APP siRNA, Wave’s Phase 1b/2a positive SELECT-HD data, 170+ biotech and 30+ pharma active in the field, and a surge of novel approaches, the oligonucleotide field shows no signs of slowing down.

The 5th Oligonucleotides for CNS Summit unites a select group of industry-leading biologists, chemists, C-level executives, platform tech experts, DMPK and clinical pharmacologists, all tackling the unique challenges of CNS delivered ASOs, siRNAs, miRNAs and saRNAs.

This August, hear from Alnylam Pharmaceuticals, Denali Therapeutics, Genentech, FDA, Novo Nordisk, Regeneron, Servier, Stoke Therapeutics, Ultragenyx Pharmaceutical and more, to redefine the landscape of oligonucleotide research.

Check Out the 2025 Agenda:

Unpublished insights and never-seen-before data

Two tracked workshop day designed for chemists and biologists

10 new presenting companies including Denali Therapeutics, Alnylam Pharmaceuticals and Novo Nordisk

Regulator presence from Ron Wange, a former FDA expert and author of the non-clinical guidance for oligonucleotides

5th Oligonucleotides for CNS Summit Brochure Cover

World-Class Speaker Faculty:

Previously Attending Companies:

58573 - previously attending companies

Hear from Your Peers:

Nicole Lykens

"This summit brings together key stakeholders, including industry leaders, researchers, and regulatory experts, to collaboratively address challenges, share innovative solutions, and explore the transformative potential of oligonucleotide therapeutics in advancing treatment options for CNS disorders" 

Nicole Lykens, Director of Neurobiology, Global Nucleic Acid Therapies (GNAT), Novo Nordisk

Jimmy Weterings

"CNS is the next frontier in ASO and RNA therapeutics. Attending this conference will provide me, and you, a front row seat to follow the latest achievements, current developments and future aspirations of companies and its stakeholders active in this exciting space" 

Jimmy Weterings, Vice President, Head of Oligonucleotide Therapeutics, Bonito Biosciences

Proud to Partner With:

Luxna Biotech
ChemGenes
Synoligo Biotechnologies
Transpharmation
Beacon = Partner - Oligos for CNS 2025

Other Events in the Series: