Puneet Anand

Company: Regeneron Pharmaceuticals

Job title: Senior Principal Scientist - Genetic Medicines

Seminars:

1:00 pm Workshop D: Refining the Next Antibody- Oligonucleotide Conjugates (AOC) & Delivery Chemistries 1:00 pm

Antibody-oligonucleotide conjugates (AOCs) represent a cutting-edge approach to improving targeted RNA therapeutics, offering enhanced precision in delivery, while overcoming key barriers such as biodistribution and cellular uptake. This workshop will focus on the latest advancements in AOC design, with a particular emphasis on brain shuttle strategies and delivery chemistry to optimize therapeutic outcomes for neurological…Read more

day: Pre-Conference Workshop Day - Track B P2

Panel Discussion: Brain Shuttles Beyond TFR1: What Will Be the Next Hot Brain Shuttle? 3:00 pm

Evaluate the opportunities in overcoming target delivery challenges with TfR1 overexpression and off-target specificity Explore small molecules, APOE1 peptides, nanopeptides, carbohydrates, LNPs as alternative ligands comparing pros, cons and negatives; evaluating opportunities where different ligands might be more ‘fit-for-purpose’Read more

day: Day 2