Muthiah (Mano) Manoharan

Company: Alnylam Pharmaceuticals

Job title: Senior Vice President, Innovation Chemistry & Alnylam Distinguished Scientist

Seminars:

Biomimetic Chemistry of siRNA Delivery to CNS 3:30 pm

Synthetic small interfering RNAs (siRNAs) are potent inhibitors of gene expression. These molecules are perfect examples of biomimetic chemistry as synthetic siRNAs act through the natural RNA interference (RNAi) pathway To deliver therapeutic siRNAs for CNS applications, we have developed approaches that include extensive chemical modification of the siRNAs and lipidic nucleic acids (siRNA-lipid conjugates)…Read more

day: Day 1