Marjie Hard

Company: Trace Neuroscience

Job title: Senior Vice President, Development Sciences

Seminars:

Advancing a Splice-Modulating ASO Restoring UNC13A protein for ALS: Nonclinical Studies Guided Optimization of the Clinical Trial Design 11:00 am

Nonclinical approach to support clinical trials with a splice modulating ASO designed to correct UNC13A mis-splicing associated with TDP-43 pathology in ALS Learnings from nonclinical studies and the path toward initiating first-inhuman trials within the year Impact of regulatory feedback on nonclinical strategy and the clinical trial design Optimizing clinical trial design and dosing strategy…Read more

day: Day 2