Bruce Morimoto

Company: Principal Consultant

Job title: Principal Consultant

Seminars:

Panel Discussion: Turning Setbacks into Success: Lessons Learned from Clinical Trial Failures to Strengthen CNS Oligonucleotide Development 9:00 am

Explore common causes of clinical trial failures in CNS oligonucleotide programs, from delivery barriers to patient heterogeneity Share strategies for improving target validation, biomarker selection, and preclinical models to better predict clinical outcomes Discuss best practices for early safety assessment, managing off-target effects, and optimizing dosing strategies Examine how aligning trial design and development plans…Read more

day: Day 1

Roundtable Discussion: Future Applications of Oligonucleotides in Neuroscience: What’s the Next Target Disease Area? 2:00 pm

Outline disease areas with recent progress and innovation, and opportunities for cross-learnings Compare multimodal oligonucleotides approaches (ASOs, siRNAs, and more), diverse conjugates mapped out against opportunities in different disease areas Assess the potential of oligonucleotides in neuropsychiatric and neurodevelopmental disorders. Can lessons from neurodegeneration be applied?Read more

day: Day 1