FAQs

The 6th Oligonucleotides for CNS Summit USA is the industry’s leading forum dedicated to advancing CNS‑targeted oligonucleotide therapeutics, including ASOs, siRNAs, saRNAs, and aptamers.

Taking place in August 2026, the meeting brings together 160+ experts across discovery, preclinical, translational, and clinical development to address the key challenges associated with delivering and developing RNA‑based therapies for neurological disorders.

The summit is focused on unlocking previously undruggable CNS targets through innovations in RNA chemistry, delivery technologies, and translational strategies, with applications across neurodegenerative, neuromuscular, rare, epileptic, and neurodevelopmental diseases.

The conference will be held in person in Boston, Massachusetts.

The Colonnade Hotel
120 Huntington Avenue
Boston, Massachusetts
USA
02116

You can expect to meet a highly technical, specialist audience, including:

• CNS biologists and RNA scientists
• Oligonucleotide chemists and DMPK experts
• Translational, preclinical, and clinical leaders
• Biopharma decision‑makers
• Delivery, BBB transport, and platform technology experts

Attending organizations include Eli Lilly, Stoke Therapeutics, Dyne Therapeutics, Creyon Bio, Quiver Bioscience, and many more.

The agenda spans the full oligonucleotide drug development lifecycle, with key themes including:

• CNS delivery and blood‑brain barrier penetration
• RNA chemistry, conjugation, and structural design
• ASO and siRNA discovery, potency, and dosing strategies
• AI‑driven target discovery and precision approaches
• Clinical development, safety, and target engagement
• Emerging modalities such as aptamers and splice‑switching oligonucleotides
• Expansion into broader CNS indications beyond rare disease

Sessions are delivered through data‑driven presentations, panel discussions, workshops, and roundtables.

This summit is intentionally designed to be:

• Deeply technical and science‑led
• Focused exclusively on oligonucleotides for CNS applications
• Cross‑functional, spanning discovery through clinical development
• Intimate in size to enable meaningful discussion and networking

With a strong emphasis on mechanistic insight, delivery innovation, and real‑world case studies, the meeting prioritizes actionable learning over high‑level theory

As a delegate, you will:

• Learn how leading organizations are advancing CNS oligonucleotide therapies
• Gain practical insights into delivery strategies, RNA chemistry, and translational challenges
• Hear real case studies from preclinical and clinical development
• Benchmark your programs against industry peers
• Network with a highly targeted scientific and commercial audience

You will leave with strategies that can be applied directly to your own CNS oligonucleotide programs.

You can register directly via the official summit website.

Multiple pass options are available. Early registration offers savings of up to $500, subject to deadlines.

Explore registration options here.

Sponsoring the summit allows you to:

• Position your company as a partner of choice in CNS oligonucleotide development
• Engage directly with decision‑makers actively seeking solutions
• Showcase your capabilities across synthesis, delivery, CRO/CDMO services, and analytics
• Access curated 1‑to‑1 meetings and high‑value networking opportunities
• Increase visibility before, during, and after the event

Partnership opportunities are fully customizable to align with your strategic goals. Explore your options here.

The summit runs from August 19–21, 2026 and includes:

• Pre‑Conference Day (Wednesday, August 19)
• Main Conference Days (August 20–21)

Yes. Group discounts are available for organizations registering multiple delegates.

Discounts apply when two or more delegates from the same company register and pay at the same time, with increased savings for larger groups.

Explore registration options here.

Yes. Discounted academic and research rates are available for full‑time academics and researchers.

Eligibility criteria apply, and bookings are subject to approval.

Explore registration options here.

For questions about registration, sponsorship, pricing, or eligibility, you can contact the team directly:

Email: info@hansonwade.com

The team will be happy to support any queries related to attending, partnering, or speaking opportunities.

For sponsor related queries: sponsor@hansonwade.com