Reduced ALN-APP for Alzheimer’s Disease & Cerebral Amyloid Angiopathy
Time: 8:00 am
day: Day 1
Details:
- Look at work upstream to reduce amyloid production
- Demonstrate target engagement with the first siRNA to be used in the brain
- Highlight preclinical findings from AD models and CAA, highlighting reduced cognitive decline in mice and reduced bleeding
- Delve into clinical data highlighting target engagement and plans for CAA