Non-Invasive Brain Delivery of Antisense Oligonucleotides
- Our presentation will focus on our novel approach to non-invasive brain delivery using G-aggregate antisense oligonucleotides
- This technology enables direct CNS targeting without invasive procedures, addressing the critical challenge of blood-brain barrier penetration for oligonucleotide therapeutics
- Our G-rich sequences form stable aggregates that enhance brain uptake and provide nuclear translocation capabilities