Julie Garlick

Company: Genentech

Job title: Principal Scientist

Seminars:

Optimizing Both Conjugate & Oligonucleotide Design for Greater Target Cell Affinity & Blood-Brain Barrier Permeability of siRNA Payload 11:00 am

Focus on ligand optimization over high throughput screenings to improve the balance of affinity for target cell with permeability across the blood-brain barrier Modify PK/PD profiles to reduce peripheral tissue distribution by improving receptor specificity to the blood-brain barrier Explore alternate regions beyond the FAB region for Transferrin Receptor mediated transcytosis across the blood-brain barrier…Read more

day: Day 1