Non-Clinical Strategies for Toxicological Evaluation of siRNA for CNS Disorders

Time: 11:30 am
day: Conference Day Two


  • Exploring considerations beyond ICH landscape in meeting regulatory expectations of siRNAs
  • Nonclinical evaluation and cross reactivity of siRNAs: tailoring for species selection in siRNA programs
  • Key parameters for toxicology studies: exploring route of administration, dosing regimen and repeat dosing for the future of patient treatment