Demonstrating Translatable Oligonucleotide Tolerability & PKPD Across In Vitro & NHP Models
Time: 11:30 am
day: Conference Day Two
Details:
- Accumulating tolerability data in vitro and in vivo to predict optimum sequence and formulation for larger species dosing
- Integrating efficient in vitro and in rodent models to better predict candidate tolerability and efficacy in higher species
- Improving in silico models to better predict human dose selection
