Julia Alterman

Company: University of Massachusetts Medical School

Job title: Assistant Professor

Seminars:

Impact of Chemistry & Formulation on siRNA Activity & Safety in the CNS 4:30 pm

• Evaluating evidence for negative charge effect and link to alterations in brain homeostasis to induce seizures • Reviewing alterations in formulation for oligo delivery to reduce impact of negatively charged compounds and minimize neurotoxicityRead more

day: Day One PM

Roundtable Discussion: Tackling CNS Adverse Event Concerns to Ameliorate Welfare in Oligo Research 4:00 pm

• Discussing tragic incidences of hydrocephalus and necessary work to understand underlying mechanism • Debating risk/benefit and morality of pushing research ahead in catastrophic neurological disease • Outlining potential long-term safety concerns of oligonucleotide therapy and strategy to addressRead more

day: Day One PM