Understanding How Route of Administration Impacts siRNA Delivery in the Central Nervous System

Time: 11:00 am
day: Day Two


  • Comparison of parenchymal, ventricular, and intrathecal siRNA administration in the CNS of multiple species
  • Effect of ROA on deep brain penetration and oligonucleotide retention
  • Relationship between accumulation and silencing and the implications for compound duration of effect